GeneTex
United States (US)

PDGF-BB recombinant protein

Cat No. GTX65196

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The ED50 as determined by the dose-dependent stimulation of thimidine uptake by BALB/c 3T3 cells is < 1 ng/ml, corresponding to a specific activity of > 1x10^6 units/mg.

Calculated MW

24.3 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or –20ºC for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

PDGF Bchain, PDGFBB, Osteosarcoma-derived Growth Factor, FLJ12858, Becaplermin., Platelet-derived growt, PDGF-BB, Gliomaderived growth factor, PDGF2, csis, Plateletderived growt, c-sis, Plateletderived growth factor beta polypeptide, PDGFB, Osteosarcomaderived Growth Factor, SIS, GDGF, ODGF, PDGF B-chain, c sis, PDGF BB, PDGF B chain, Platelet derived growt

Background

Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF, which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer. Human PDGF-BB is a 24.3 kDa B chain homodimer protein formed by subunits of 109 amino acid residues.

Research Area