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PEVR2 antibody

Anti-PEVR2 antibody used in Western Blot (WB). GTX87668
Anti-PEVR2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87668

Cat. No. GTX87668

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μg ($399)
See all PEVR2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
ICC/IF 1:100~1:500
Not tested in other applications.

Calculated MW

46 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human PEVR2 (235-284).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

RRID

AB_10722011

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

GPCR42 , GPR172B , PAR2 , RBFVD , RFT1 , RFVT1 , SLC52A1 , hRFT1 , solute carrier family 52 member 1 , PEVR2 , solute carrier family 52 (riboflavin transporter), member 1

Cellular Localization

Cell membrane

Background

Biological redox reactions require electron donors and acceptor. Vitamin B2 is the source for the flavin in flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) which are common redox reagents. This gene encodes a member of the riboflavin (vitamin B2) transporter family. Haploinsufficiency of this protein can cause maternal riboflavin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2013]

Database

Research Area

DATA IMAGES

Anti-PEVR2 antibody used in Western Blot (WB). GTX87668

GTX87668 WB Image

WB analysis of LOVO cell lysates using GTX87668 PEVR2 antibody. The lane on the right is blocked with the synthesized peptide.

Anti-PEVR2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87668

GTX87668 ICC/IF Image

ICC/IF analysis of MCF7 cells using GTX87668 PEVR2 antibody. The picture on the right is blocked with the synthesized peptide.

REFERENCE

Application Reference

Alessia Niceforo et al. Dis Model Mech 2021; Altered cytoskeletal arrangement in induced pluripotent stem cells (iPSCs) and motor neurons from patients with riboflavin transporter deficiency.
Application : ICC/IF
Reactivity : Human
Anandam KY et al. Am J Physiol Cell Physiol 2018; 315 (5) : C653-C663 Effect of the Proinflammatory Cytokine TNF-α on Intestinal Riboflavin Uptake: Inhibition Mediated via Transcriptional Mechanism(s).
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399