GeneTex

  • Country / Location Selection

United States (US)

PIN1 antibody [3G8]

Anti-PIN1 antibody [3G8] used in Western Blot (WB). GTX53762

Cat. No. GTX53762

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3G8

Isotype

 IgG1

Application

 WB, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all PIN1 products

APPLICATION

Application Note

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.

Calculated MW

18 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human PIN1 (1-163aa) purified from E. coli

Purification

By protein-G affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

peptidylprolyl cis/trans isomerase, NIMA-interacting 1 , DOD , UBL5

Cellular Localization

Nucleus , Nucleus speckle , Cytoplasm

Background

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]

Database

Research Area

DATA IMAGES

Anti-PIN1 antibody [3G8] used in Western Blot (WB). GTX53762

GTX53762 WB Image

WB analysis of 293T, HeLa and Jurkat lysates (50ug per lane) using Pin1 antibody at a dilution of 1:500.

REFERENCE

There are currently no references for PIN1 antibody [3G8] (GTX53762). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for PIN1 antibody [3G8] (GTX53762). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399