GeneTex
United States (US)

PLGF-1 recombinant protein

Cat No. GTX65200

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

Protein's bioactivity determined by its ability to chemoattract human monocytes of using a concentration range of 0.5-10 ng/ml.

Calculated MW

29.7 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute the protein in sterile 20 mM acetic acid to a concentration of 0.1-1.0 mg/mL. Store at -20ºC.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥95%) and by HPLC (≥95%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

PLGF 1, PGF, Placenta Growth Factor1, PIGF, Placenta Growth Factor-1, PLGF1, Placenta Growth Factor 1

Background

PLGF (also called Placenta Growth Factor, PIGF, PGF) is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant 22 PLGF is a disulfide-linked homodimer containing two 142 amino acid polypeptide chains.

Research Area