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PMP22 antibody

Anti-PMP22 antibody used in IHC (Paraffin sections) (IHC-P). GTX15506
Anti-PMP22 antibody used in IHC (Paraffin sections) (IHC-P). GTX15506

Cat. No. GTX15506

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($399)
See all PMP22 products

APPLICATION

Application Note

IHC-P: Use at a dilution of 1/50 for 10 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0 for 10 minutes, followed by cooling at RT for 20 minutes. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

18 kDa. ( Note )

Positive Control

Pancreas

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal).

Purification

Immunogen affinity purified

Conjugation

Unconjugated

RRID

AB_370706

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

peripheral myelin protein 22 , CIDP , CMT1A , CMT1E , DSS , GAS-3 , GAS3 , HMSNIA , HNPP , Sp110

Cellular Localization

Cell membrane

Background

This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Database

Research Area

DATA IMAGES

Anti-PMP22 antibody used in IHC (Paraffin sections) (IHC-P). GTX15506

GTX15506 IHC-P Image

GTX15506 staining PMP22 in human pancreas by Immunohistochemistry (FFPE-sections).

Anti-PMP22 antibody used in IHC (Paraffin sections) (IHC-P). GTX15506

GTX15506 IHC-P Image

Human Pancreas stained with anti-Peripheral Myelin Protein (PMP-22) antibody (GTX15506)

REFERENCE

Application Reference

Naik AK et al. Anesth Analg 2012; 114 (3) : 674-82 Dorsal root ganglion application of muscimol prevents hyperalgesia and stimulates myelin protein expression after sciatic nerve injury in rats.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399