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PMS2 antibody [163C1251]

Anti-PMS2 antibody [163C1251] used in Western Blot (WB). GTX13900
Anti-PMS2 antibody [163C1251] used in IHC (Paraffin sections) (IHC-P). GTX13900

Cat. No. GTX13900

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 163C1251

Isotype

 IgG1

Application

 WB, IHC-P, FACS, MS

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all PMS2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/ml
IHC-P 2 - 5μg/ml
FACS 1μg / 10⁶ cells
MS Assay dependent
Not tested in other applications.

Calculated MW

96 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 623-639 SSLAKRIKQLHHEAQQS of human PMS2; GenBank No. NP_000526.1.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

PMS1 homolog 2, mismatch repair system component , HNPCC4 , MLH4 , PMS2CL , PMSL2

Cellular Localization

Nucleus

Background

This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-PMS2 antibody [163C1251] used in Western Blot (WB). GTX13900

GTX13900 WB Image

WB analysis of NIH-3T3 cell lysate using GTX13900 PMS2 antibody [163C1251].
Dilution : 2 μg/ml

Anti-PMS2 antibody [163C1251] used in IHC (Paraffin sections) (IHC-P). GTX13900

GTX13900 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX13900 PMS2 antibody [163C1251].
Dilution : 5 μg/ml
Antigen retrieval : Heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0)

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399