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PRMT3 antibody

KO/KD Orthogonal
Anti-PRMT3 antibody used in IHC (Paraffin sections) (IHC-P). GTX23765
Anti-PRMT3 antibody used in Western Blot (WB). GTX23765
Anti-PRMT3 antibody used in IHC (Paraffin sections) (IHC-P). GTX23765
Anti-PRMT3 antibody used in Western Blot (WB). GTX23765
Anti-PRMT3 antibody used in Western Blot (WB). GTX23765
Anti-PRMT3 antibody used in Western Blot (WB). GTX23765
Anti-PRMT3 antibody used in Immunohistochemistry (IHC). GTX23765
Anti-PRMT3 antibody used in Western Blot (WB). GTX23765

Cat. No. GTX23765

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IHC

Reactivity

 Human
Package
400 μl ($399)
See all PRMT3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:50-1:100
IHC Assay dependent
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

Predict Reactivity

Mouse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 460-491 amino acids from the C-terminal region of human PRMT3.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

RRID

AB_372826

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

protein arginine methyltransferase 3 , HRMT1L3

Cellular Localization

Cytoplasm

Background

This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo substrate, and is involved in the proper maturation of the 80S ribosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Database

Research Area

DATA IMAGES

Anti-PRMT3 antibody used in IHC (Paraffin sections) (IHC-P). GTX23765

GTX23765 IHC-P Image

IHC-P analysis of human breast carcinoma using GTX23765 PRMT3 antibody.

Anti-PRMT3 antibody used in Western Blot (WB). GTX23765

GTX23765 WB Image

WB analysis of HL-60 cell lysate using GTX23765 PRMT3 antibody.

Anti-PRMT3 antibody used in IHC (Paraffin sections) (IHC-P). GTX23765

GTX23765 IHC-P Image

IHC-P analysis of human prostata carcinoma tissue using GTX23765 PRMT3 antibody.

Anti-PRMT3 antibody used in Western Blot (WB). GTX23765

GTX23765 WB Image

Orthogonal

The data was published in the journal Cancers (Basel) in 2018. PMID: 30577570

Anti-PRMT3 antibody used in Western Blot (WB). GTX23765

GTX23765 WB Image

KO/KD

The data was published in the journal J Hematol Oncol in 2019.PMID: 31324208

Anti-PRMT3 antibody used in Western Blot (WB). GTX23765

GTX23765 WB Image

KO/KD

The data was published in the journal Cancers (Basel) in 2018. PMID: 30577570

Anti-PRMT3 antibody used in Immunohistochemistry (IHC). GTX23765

GTX23765 IHC Image

The data was published in the journal Cancers (Basel) in 2018. PMID: 30577570

Anti-PRMT3 antibody used in Western Blot (WB). GTX23765

GTX23765 WB Image

The data was published in the journal J Hematol Oncol in 2019.PMID: 31324208

REFERENCE

Application Reference

Hsu MC et al. J Hematol Oncol 2019; 12 (1) : 79 Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer.
Application : WB
Reactivity : Human
Hsu MC et al. Cancers (Basel) 2018; 11 (1) Protein Arginine Methyltransferase 3 Enhances Chemoresistance in Pancreatic Cancer by Methylating hnRNPA1 to Increase ABCG2 Expression.
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399