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PRX II antibody

Anti-PRX II antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX15572

Cat. No. GTX15572

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human
Package
50 μl ($399)
See all PRX II products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:10,000
ICC/IF 1:500
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

Product Note

This antibody is specific for Prx 2 and shows no cross-reactivity with other Prx isoforms.

PROPERTIES

Form

Liquid

Buffer

Serum

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to residues L(104) L A D V T R R L S E D(115) of human Peroxiredoxin 2.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

peroxiredoxin 2 , HEL-S-2a , NKEF-B , NKEFB , PRP , PRX2 , PRXII , PTX1 , TDPX1 , TPX1 , TSA

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]

Database

Research Area

DATA IMAGES

Anti-PRX II antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX15572

GTX15572 ICC/IF Image

ICC/IF analysis of TSU-Pr1 cells using GTX15572 PRX II antibody.

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399