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PSAP antibody

Anti-PSAP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54581
Anti-PSAP antibody used in IHC (Paraffin sections) (IHC-P). GTX54581
Anti-PSAP antibody used in Western Blot (WB). GTX54581
Anti-PSAP antibody used in IHC (Paraffin sections) (IHC-P). GTX54581
Anti-PSAP antibody used in IHC (Paraffin sections) (IHC-P). GTX54581

Cat. No. GTX54581

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all PSAP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 60-310 of human PSAP (NP_002769.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

prosaposin , GLBA , SAP1

Cellular Localization

Lysosome

Background

This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Database

Research Area

DATA IMAGES

Anti-PSAP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54581

GTX54581 ICC/IF Image

ICC/IF analysis of MCF7 cells using GTX54581 PSAP antibody.
Blue : DAPI

Anti-PSAP antibody used in IHC (Paraffin sections) (IHC-P). GTX54581

GTX54581 IHC-P Image

IHC-P analysis of rat brain tissue using GTX54581 PSAP antibody.
Dilution : 1:200

Anti-PSAP antibody used in Western Blot (WB). GTX54581

GTX54581 WB Image

WB analysis of various sample lysates using GTX54581 PSAP antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

Anti-PSAP antibody used in IHC (Paraffin sections) (IHC-P). GTX54581

GTX54581 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX54581 PSAP antibody.
Dilution : 1:200

Anti-PSAP antibody used in IHC (Paraffin sections) (IHC-P). GTX54581

GTX54581 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX54581 PSAP antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399