GeneTex
United States (US)

PTHrP recombinant protein

Cat No. GTX65225

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Calculated MW

9.8 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute in water to a concentration 0.1-1 mg/ml. The solution can then be further diluted to other aqueous solutions. Store at -20ºC.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

MGC138426, PTHLH, MGC138452, PTH/PTHrP receptor antagonist, PTHrP analog, PTHR

Background

Parathyroid Hormone-like related Protein (PTHrP) is a member of the Parathyroid hormone family that is expressed in the mammary gland. It is known as a potent inhibitor of chondrocyte maturation. PTHrP is expressed by periarticular perichondrial cells and exerts its biological activity on PP-R expressing cells. During endochondral bone development PTHrP plays a major role in suppressing the onset of hypertrophic differentiation. It is also responsible for most cases of humoral hypercalcemia of malignancy. Recombinant Human PTHrP is a 9.8 kDa protein consisting of 86 amino acid residues.

Research Area