APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
4 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Japanese Medaka, Elephant, Gibbon, Gorilla, Marmoset, Opossum, Panda, Pufferfish, Turkey, Platypus, Sea bass, Stickleback(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 18 amino acid peptide from cytoplasmic domain of human PTPRA.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
protein tyrosine phosphatase receptor type A , HEPTP , HLPR , HPTPA , HPTPalpha , LRP , PTPA , PTPRA , PTPRL2 , RPTPA , RPTPalpha , protein tyrosine phosphatase, receptor type A , PTP alpha
Cellular Localization
Membrane
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX13095 IHC-P Image
IHC-P analysis of human breast, epithelium tissue using GTX13095 PTPRA antibody. Antigen retrieval : Heat-induced antigen retrieval Dilution : 4 μg/ml
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GTX13095 IHC-P Image
IHC-P analysis of human skeletal muscle tissue using GTX13095 PTPRA antibody. Antigen retrieval : Heat-induced antigen retrieval Dilution : 4 μg/ml
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REFERENCE
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REVIEW
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