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Pleiotrophin antibody

Cat. No. GTX10849

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ELISA

Reactivity

 Human
Package
50 μg ($399)
See all Pleiotrophin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.2 μg/ml
ELISA 1:200
Not tested in other applications.

Calculated MW

19 kDa. ( Note )

Positive Control

female Lewis rats cutaneous nerve protein

PROPERTIES

Form

Liquid

Buffer

PBS, 5% Trehalose

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

purified recombinant human pleiotrophin expressed in Sf 21 cells.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

pleiotrophin , HARP , HB-GAM , HBBM , HBGF-8 , HBGF8 , HBNF , HBNF-1 , NEGF1 , OSF-1

Cellular Localization

Secreted

Background

Human pleiotrophin is produced by a 168 amino acid residue PTN precursor. A 136 amino acid residue mature recombinant human pleiotrophin results from removal of the 32 amino acid residue signal peptide. Recombinant PTN has a predicted molecular mass of approximately 15.3 kDa. In SDS-PAGE, it migrates as an 18 kDa band, which may be due to its high lysine content. Pleiotrophin is highly conserved; human, bovine, rat, and mouse PTN share >98% amino acid sequence homology. Pleiotrophin is a member of a family of heparin-binding, developmentally regulated cytokines. It is active in growth and development and has mitogenic and neurite outgrowth activity. The gene for pleiotrophin is highly expressed in brain, uterus, gut, muscle,lung, and skin tissues. Pleiotrophin mRNA is expressed in osteoblasts, chondrocytes, fibroblasts, astrocytes, Schwann cells, and tumor cells.

Database

Research Area

REFERENCE

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SDS
PBS.pdf
Package List Price ($)
$ 399