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Prosapip1 antibody

Anti-Prosapip1 antibody used in IHC (Paraffin sections) (IHC-P). GTX85249
Anti-Prosapip1 antibody used in Western Blot (WB). GTX85249
Anti-Prosapip1 antibody used in IHC (Paraffin sections) (IHC-P). GTX85249

Cat. No. GTX85249

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all ProSAPiP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

Positive Control

SK-N-SH Cell Lysate(GTX23956)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Prosapip1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Prosapip1.The immunogen is located within amino acids 590 - 640 of Prosapip1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

leucine zipper tumor suppressor family member 3 , PROSAPIP1

Cellular Localization

Cell junction, synapse,Cytoplasm, cytoskeleton

Background

Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3’s PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed ‘Fezzins’. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.

Database

Research Area

DATA IMAGES

Anti-Prosapip1 antibody used in IHC (Paraffin sections) (IHC-P). GTX85249

GTX85249 IHC-P Image

IHC-P analysis of rat brain tissue using GTX85249 Prosapip1 antibody.
Working concentration : 2.5 μg/ml

Anti-Prosapip1 antibody used in Western Blot (WB). GTX85249

GTX85249 WB Image

WB analysis of SK-N-SH cell lysate using GTX85249 Prosapip1 antibody.
Working concentration : 1 μg/ml

Anti-Prosapip1 antibody used in IHC (Paraffin sections) (IHC-P). GTX85249

GTX85249 IHC-P Image

IHC-P analysis of rat brain tissue using GTX85249 Prosapip1 antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399