GeneTex
United States (US)

RANK (sRANKL) recombinant protein

Cat No. GTX65291

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is <10 ng/ml.

Calculated MW

20.0 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Buffer

5 mM Tris, pH 7.6 + 75 mM NaCl

Storage

Reconstitute in water to a concentration of 0.1-1.0 mg /ml. The solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or –20ºC for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Osteoprotegerin ligand, Tumor necrosis factor ligand superfamily member11, TNFSF11, sRANKL, ODF, TNF-related activation-induced cytokine, OPGL, RANK, TNFrelated activationinduced cytokine, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, Osteoclast differentiation factor, TRANCE

Background

Human RANK (receptor activator of NF-kB) is a member of the TNFR family, identified as a dentritic cell membrane protein. Human soluble RANK Ligand is a soluble 20.0 kDa polypeptide, comprising the TNF homologous region of RANKL (176 amino acid residues).

Research Area

Package List Price ($)
$ 529