10 mM Tris, pH 7.5 + 25 mM NaCl.
Reconstitute in water to a concentration of 0.1-1. Reconstitute in ddH2O. Store at -20ºC. Product is stable for at least 12 months.
Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Cysteinerich secreted protein A12gamma, Parasite-induced macrophage novel gene 1 protein, Cysteine-rich secreted protein A12-gamma, Cysteinerich secreted, Cysteinerich secreted protein FIZZ1, RELM-a, Resistin-like alpha, RELMa, RETNA, Cysteine-rich secreted, Resistinlike alpha, Parasiteinduced macrophage novel gene1 protein, RELM a, Resistin like alpha, Cysteine rich secreted
RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-alpha re still unknown. Recombinant murine RELM-alpha is a 10.0 kDa monomeric protein containing 88 amino acid residues.