GeneTex
United States (US)

Rabies virus antibody [0.N.541]

Cat No. GTX15015

Host Mouse
Clonality Monoclonal
Clone Name 0.N.541
Isotype IgG2b
Application ELISA, Neut
Reactivity Rabies virus
APPLICATION

Application Note

For ELISA: Use at an assay dependent dilution. For Neut: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.

Specificity/Sensitivity

Reacts with viral glycoprotein of rabies virus strains SAD-Vnukovo and Pitman-Moore neutralizing these rabies strains.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline, pH 7.4, containing no preservatives

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Rabies virus of the SAD-Vnukovo and Pitman Moore strains.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Background

Rabies virus (Neurotropic lyssavirus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumblike glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Virus infectivity is destroyed by lipid solvents. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.

Research Area

Package List Price ($)
$ 329