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Rattin antibody

Cat No. GTX70483

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ELISA
Package
100 μg ($289)

APPLICATION

Application Note

Western blot - Use at 1:500 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Specificity/Sensitivity

Reacts with residues 20-35 [VKRLESPNKTRRPYGA] of the Rattin peptide, which is not in the conserved region to Humanin.

PROPERTIES

Form

Liquid

Buffer

PBS containing 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Purification

Affinity purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Background

A novel rat gene, Rattin, encodes a peptide homologous to Humanin, a secreted peptide that specifically protects against neuronal cell death induced by beta-amyloid peptide (Ab) or by mutations causing early-onset familial Alzheimer's disease. Rattin is the prototype of a novel class of peptides, phylogenetically related to Humanin, endowed with protective activity not only against Ab but also toward excitotoxic neuronal death. The rat gene, Rattin, encodes a peptide of 38 residues (15 residues longer than Humanin) showing 73% identity in the conserved region to Humanin.

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 289