GeneTex
United States (US)

SKP1 antibody

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Cat No. GTX30790

Host Mouse
Clonality Monoclonal
Clone Name 3G222
Isotype IgG1
Application WB, IP, ELISA
Reactivity Human
APPLICATION

Application Note

Recommended Starting Dilutions:
For ELISA: Use at a concentration of 0.1-1.0ug/mL.
For IP : Use at a concentration of 5-10ug/ml.
For WB: USe at a concentration of 1-3ug/ml.
Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

19 kDa. ( Note )

Positive Control

HeLa cervical carcinoma, Jurkat leukemia T cell and Wi-38 lung broblast cell lysates

Specificity/Sensitivity

Recognizes human SKP1 (p19) protein at 19kD
PROPERTIES

Form

Liquid

Buffer

PBS, pH 7.4 contianing 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human SKP1 (p19) protein

Purification

Protein A affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

S-Phase Kinase Associated Protein 1,Emc19,Ocp-Ii,Ocp2,Skp1A,Tceb1L,P19A,Skp1

Background

Skp1 is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. It is also involved in the control of beta-catenin levels the activity of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor.

Database

Research Area

DATA IMAGES
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GTX30790 Image


Package List Price ($)
$ 319