APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.5 μg/mL |
2.5 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Brain Tissue Slide(GTX22203) , Mouse Brain Tissue Lysate(GTX27934)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
SLC39A7 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human SLC39A7.The immunogen is located within amino acids 20 - 70 of SLC39A7.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
solute carrier family 39 member 7 , D6S115E , D6S2244E , H2-KE4 , HKE4 , KE4 , RING5 , ZIP7
Background
The zinc transporter ZIP7, also known as SLC39A7, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP7 was initially identified while characterizing genes in the major histocompatibility complex on chromosome 17. ZIP7 mRNA is abundantly and widely expressed and the protein localizes to the Golgi apparatus. It functions to transport intracellular zinc from the Golgi apparatus to the cytoplasm of the cell. ZIP7 expression is expressed by zinc. ZIP7 has been suggested to act a hub for tyrosine kinase activation and may thus be a potential therapeutic target for diseases such as cancer where prevention of tyrosine kinase activation would be advantageous.
Database
Research Area
DATA IMAGES
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GTX85130 IHC-P Image
IHC-P analysis of human brain tissue using GTX85130 SLC39A7 antibody. Working concentration : 2.5 μg/ml
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GTX85130 IHC-P Image
IHC-P analysis of human brain tissue using GTX85130 SLC39A7 antibody. Working concentration : 20 μg/ml
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GTX85130 WB Image
WB analysis of mouse brain tissue lysate using GTX85130 SLC39A7 antibody. Working concentration : 0.5 μg/ml
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REFERENCE
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REVIEW
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