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SOD1 antibody

KO/KD Orthogonal
Anti-SOD1 antibody used in IHC (Paraffin sections) (IHC-P). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in IHC (Paraffin sections) (IHC-P). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in ELISA (ELISA). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Anti-SOD1 antibody used in Western Blot (WB). GTX100554

Cat. No. GTX100554

Reference 66
2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, ELISA, Sandwich ELISA

Reactivity

 Human, Mouse, Rat, Alligator, Bird
Package
100 μl ($399),
25 μl ($169)
See all SOD1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:10000
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
ELISA 1:1000-1:10000
Sandwich ELISA Assay dependent

Note :

Sandwich ELISA
Capture: GTX100554 , Detection: GTX89049
Not tested in other applications.

Calculated MW

16 kDa. ( Note )

Positive Control

mouse brain , Rat brain , NT2D1 , 293T

Predict Reactivity

Rabbit, Pig, Chimpanzee, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.15 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human SOD1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10618670

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

superoxide dismutase 1 , ALS , ALS1 , HEL-S-44 , IPOA , SOD , hSod1 , homodimer

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-SOD1 antibody used in IHC (Paraffin sections) (IHC-P). GTX100554

GTX100554 IHC-P Image

Immunofluorescence photomicrographs of paraffin-embedded mouse fetal brain.
Green: SOD1 antibody (GTX100554) diluted at 1:200. The signal was developed using goat anti-rabbit IgG antibody (Dylight488) (GTX213110-04).
Red: beta Tubulin 3/ TUJ1 antibody [GT11710] diluted at 1:100. The signal was developed using goat anti-mouse IgG antibody (Dylight594) (GTX213111-05).
Blue: Nuclear staining with Hoechst 33342.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

KO/KD

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with SOD1 antibody (GTX100554) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

SOD1 antibody detects SOD1 protein by western blot analysis. Whole cell extracts (30 μg) was separated by 15% SDS-PAGE, and the membrane was blotted with SOD1 antibody (GTX100554) at a dilution of 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

Sample (50 μg of whole cell lysate)
A: Rat brain
15% SDS PAGE
GTX100554 diluted at 1:1000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

Various whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with SOD1 antibody (GTX100554) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-SOD1 antibody used in IHC (Paraffin sections) (IHC-P). GTX100554

GTX100554 IHC-P Image

SOD1 antibody detects SOD1 protein at cytosol on mouse fore brain by immunohistochemical analysis.
Sample: Paraffin-embedded mouse fore brain.
SOD1 antibody (GTX100554) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

Sample (50 μg of whole cell lysate)
A: mouse brain
15% SDS PAGE
GTX100554 diluted at 1:1000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-SOD1 antibody used in ELISA (ELISA). GTX100554

GTX100554 ELISA Image

ELISA detection of SOD1 using GTX100554 for capture at a concentration of 5 μg/mL and GTX89049 for detection at a concentration of 1.5 μg/mL.

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

Orthogonal

The data was published in the journal Nutrients in 2018.PMID: 30200495

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

Orthogonal

The data was published in the journal Front Neurol in 2019.PMID: 31258504

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

Orthogonal

The data was published in the journal PLoS One in 2014. PMID: 25551569

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

The data was published in the journal Reprod Biol Endocrinol in 2018. PMID: 29316934

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

The data was published in the journal Reprod Biol Endocrinol in 2018. PMID: 29316934

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

The data was published in the journal Reprod Biol Endocrinol in 2018. PMID: 29316934

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

The data was published in the journal Sci Rep in 2017. PMID: 29215072

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

The data was published in the journal Sci Rep in 2017. PMID: 29215072

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

The data was published in the journal Sci Rep in 2017. PMID: 29215072

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

The data was published in the journal Heliyon in 2018. PMID: 30533548

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

The data was published in the journal Heliyon in 2018. PMID: 30533548

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

The data was published in the journal Front Physiol in 2019. PMID: 31040795

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

The data was published in the journal Heliyon in 2018. PMID: 30533548

Anti-SOD1 antibody used in Western Blot (WB). GTX100554

GTX100554 WB Image

The data was published in the journal PLoS One in 2016. PMID: 27537547

REFERENCE

Application Reference

Amesaka H et al. Protein Sci 2024; 33 (4) : e4961 Engineering a monobody specific to monomeric Cu/Zn-superoxide dismutase associated with amyotrophic lateral sclerosis.
WJ Chen et al. J Food Biochem 2024; : 6676977 Liquid-State Fermented Ganoderma lucidum GANO99 Regulates Gut Microbiota and Concomitantly Modulates the Behavioral Deficits and Neurohistopathological Hallmarks of Alzheimer’s Disease in a Preclinical Transgenic Mouse Model of Alzheimer’s Disease
Application : IHC-P
Yammine A et al. Curr Res Toxicol 2024; 6 : 100153 Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol - Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue.
A Yammine et al. CRTOX 2024; 6 : 100153 Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol – Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue
Ayoubi R et al. F1000Res 2023; 12 : 391 Identification of high-performing antibodies for Superoxide dismutase [Cu-Zn] 1?(SOD1) for use in Western blot, immunoprecipitation, and immunofluorescence.
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Submit a Reference

REVIEW

SOD1 antibody Cat. No. GTX100554

Rating
( Average 4.5 based on 2 users reviews)
Application
Western Blot(WB)
( Average 4.5 based on 2 users reviews)
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Date : Anonymous submitted on 26-Jul-2022
Score :
Application Tested : WB
Sample Species : Hu
Sample : HeLa WT and SOD1 KO cells
Amount used : 20μg
Blocking : 5% milk, 1 hr
Primary Antibody : 1:1000 in 5% BSA and TBST, 4°C, > 12Hr
Figure Note : Data provided by YCharOS Inc., an open science company with the mission of characterizing commercially available antibody reagents for all human proteins using knockout technology.
Anti-SOD1 antibody used in Western Blot (WB). GTX100554
Date : Anonymous submitted on 22-Apr-2013
Score :
Application Tested : WB
Sample Species : Hu
Sample : F79 cells,F123 cells
Amount used : 40μg
Blocking : 5% non-fat milk, 25°C, 1Hr
Primary Antibody : 1:2000, 4°C, 16Hr
Submit a Review
Application Reference
Amesaka H et al. Protein Sci 2024; 33 (4):e4961 Engineering a monobody specific to monomeric Cu/Zn-superoxide dismutase associated with amyotrophic lateral sclerosis.
WJ Chen et al. J Food Biochem 2024;:6676977 Liquid-State Fermented Ganoderma lucidum GANO99 Regulates Gut Microbiota and Concomitantly Modulates the Behavioral Deficits and Neurohistopathological Hallmarks of Alzheimer’s Disease in a Preclinical Transgenic Mouse Model of Alzheimer’s Disease
Application : IHC-P
Yammine A et al. Curr Res Toxicol 2024; 6:100153 Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol - Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue.
A Yammine et al. CRTOX 2024; 6:100153 Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol – Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue
Ayoubi R et al. F1000Res 2023; 12:391 Identification of high-performing antibodies for Superoxide dismutase [Cu-Zn] 1?(SOD1) for use in Western blot, immunoprecipitation, and immunofluorescence.
Kogami M et al. Oncol Lett 2023; 26 (1):313
Mariko Kogami et al. Oncol. Lett. 2023; 26:313
Application : WB
Reactivity : Human
Brinks R et al. Antioxidants (Basel) 2023; 12 (3) Nrf2 Activation Does Not Protect from Aldosterone-Induced Kidney Damage in Mice.
Application : WB
Reactivity : Mouse
Baek Y et al. Commun Biol 2022; 5 (1):1085 Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation.
Application : ICC/IF
Reactivity : Human
Mesquita PHC et al. Physiol Rep 2022; 10 (24):e15542 Effects of aging and long-term physical activity on mitochondrial physiology and redox state of the cortex and cerebellum of female rats.
Ramos H et al. Antioxidants (Basel) 2022; 11 (7) Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy.
Wu YL et al. Antioxidants (Basel) 2022; 11 (7) In Vitro Efficacy and Molecular Mechanism of Curcumin Analog in Pathological Regulation of Spinocerebellar Ataxia Type 3.
Erna Sulistyowati et al. Int J Mol Sci 2022; 23 (10) Potential Actions of Baicalein for Preventing Vascular Calcification of Smooth Muscle Cells In Vitro and In Vivo.
Application : WB
Reactivity : Rat
Asli E Dogan et al. J Biol Chem 2022; 298 (7):102050 PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c.
Tsai-Chun Lai et al. Part Fibre Toxicol 2022; 19 (1):25 Combined exposure to fine particulate matter and high glucose aggravates endothelial damage by increasing inflammation and mitophagy: the involvement of vitamin D.
Application : WB
David E Lee et al. JCSM Rapid Commun 2021; 4 (1):3月15日 Cancer-induced Cardiac Atrophy Adversely Affects Myocardial Redox State and Mitochondrial Oxidative Characteristics.
Application : WB
Reactivity : Mouse
Woo TG et al. Commun Biol 2021; 4 (1):1397 Novel chemical inhibitor against SOD1 misfolding and aggregation protects neuron-loss and ameliorates disease symptoms in ALS mouse model.
Application : WB
Reactivity : Mouse
Lim S et al. J Appl Physiol (1985) 2021; Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice.
Application : WB
Reactivity : Mouse
Chien LH et al. Antioxidants (Basel) 2021; 10 (10)
Application : WB
Reactivity : Mouse
Lin HY et al. Free Radic Biol Med 2021; 172:430-440 17β-estradiol induces temozolomide resistance through NRF2-mediated redox homeostasis in glioblastoma.
Jiang WP et al. Antioxidants (Basel) 2021; 10 (6) Sanghuangporus sanghuang Mycelium Prevents Paracetamol-Induced Hepatotoxicity through Regulating the MAPK/NF-κB, Keap1/Nrf2/HO-1, TLR4/PI3K/Akt, and CaMKKβ/LKB1/AMPK Pathways and Suppressing Oxidative Stress and Inflammation.
Application : WB
Reactivity : Mouse
Mesquita PHC et al. Antioxidants (Basel) 2021; 10 (3) Effects of Resistance Training on the Redox Status of Skeletal Muscle in Older Adults.
Application : WB
Reactivity : Human
Rosa-Caldwell ME et al. Int J Mol Sci 2020; 21 (21) Mitochondrial Function and Protein Turnover in the Diaphragm are Altered in LLC Tumor Model of Cancer Cachexia.
Balhorn R et al. Int J Mol Sci 2020; 21 (13) Aldosterone Induces DNA Damage and Activation of Nrf2 Mainly in Tubuli of Mouse Kidneys.
Yammine A et al. Cells 2020; 9 (11) Prevention by Dietary Polyphenols (Resveratrol, Quercetin, Apigenin) Against 7-Ketocholesterol-Induced Oxiapoptophagy in Neuronal N2a Cells: Potential Interest for the Treatment of Neurodegenerative and Age-Related Diseases.
Application : WB
Reactivity : Mouse
Ramos H et al. Antioxidants (Basel) 2020; 9 (9)
Application : WB
Reactivity : Mouse
Muzio L et al. Nat Commun 2020; 11 (1):3848 Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis.
Application : WB
Reactivity : Mouse
Park NR et al. J Comp Physiol B 2020; 190 (4):465-477 Mitochondrial physiology varies with parity and body mass in the laboratory mouse (Mus musculus).
Application : WB
Reactivity : Mouse
Huang CY et al. Nutrients 2020; 12 (6) Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy.
Application : WB
Reactivity : Mouse
Chen JF et al. J Pharm Biomed Anal 2020; 187:113142 Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells.
Application : WB
Reactivity : Human
Gatz C et al. Front Neurol 2019; 10:562 Identification of Cellular Pathogenicity Markers for SIL1 Mutations Linked to Marinesco-Sj?gren Syndrome.
Application : WB
Reactivity : Human
Parry HA et al. Front Physiol 2019; 10:436 Bovine Milk Extracellular Vesicles (EVs) Modification Elicits Skeletal Muscle Growth in Rats.
Huang SY et al. Biomolecules 2019; 9 (8) The Protective Effect of Hispidin against Hydrogen Peroxide-Induced Oxidative Stress in ARPE-19 Cells via Nrf2 Signaling Pathway.
Application : WB
Reactivity : Human
Jia D et al. J Cell Physiol 2019; (Epub) Postinfarction exercise training alleviates cardiac dysfunction and adverse remodeling via mitochondrial biogenesis and SIRT1/PGC-1帢/PI3K/Akt signaling.
Application : WB
Reactivity : Rat
Wu CT et al. Oxid Med Cell Longev 2019; 2019:9056845 Salvianolic Acid C against Acetaminophen-Induced Acute Liver Injury by Attenuating Inflammation, Oxidative Stress, and Apoptosis through Inhibition of the Keap1/Nrf2/HO-1 Signaling.
Application : WB
Reactivity : Mouse
Hyatt HW et al. Reprod Biol Endocrinol 2018; 16 (1):2 Physiological, mitochondrial, and oxidative stress differences in the presence or absence of lactation in rats.
Hsieh YH et al. Nutrients 2018; 10 (9) Ginsenoside Rh2 Ameliorates Lipopolysaccharide-Induced Acute Lung Injury by Regulating the TLR4/PI3K/Akt/mTOR, Raf-1/MEK/ERK, and Keap1/Nrf2/HO-1 Signaling Pathways in Mice.
Gentile D et al. Front Pharmacol 2018; 9:1094 Luteolin Prevents Cardiometabolic Alterations and Vascular Dysfunction in Mice With HFD-Induced Obesity.
Parry HA et al. Heliyon 2018; 4 (11):e00975 Ketogenic diet increases mitochondria volume in the liver and skeletal muscle without altering oxidative stress markers in rats.
Kornelius E et al. J Cell Mol Med 2018; (Epub) Liraglutide protects against glucolipotoxicity-induced RIN-m5F β-cell apoptosis through restoration of PDX1 expression.
Application : WB
Reactivity : Rat
Daniela Gentile et al. Front. Pharmacol. 2018; (Epub) Luteolin Prevents Cardiometabolic Alterations and Vascular Dysfunction in Mice With HFD-Induced Obesity.
Application : WB
Reactivity : Mouse
Pei-Ying Li et al. RSC Adv. 2018; 8:31515-31528 Alpinumisoflavone attenuates lipopolysaccharide-induced acute lung injury by regulating the effects of anti-oxidation and anti-inflammation both in vitro and.
Application : WB
Reactivity : Mouse
Cao K et al. J Clin Pathol 2018; (Epub) Reduced expression of SIRT1 and SOD-1 and the correlation between these levels in various regions of the brains of patients with Alzheimer's disease.
Application : IHC-P
Reactivity : Human
Wu CC et al. Redox Biol 2018; 19:74-80 Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress.
Application : WB
Reactivity : Mouse
Liu L et al. Am J Physiol Gastrointest Liver Physiol 2018; (Epub) Hepatic ZIP8 deficiency is associated with disrupted selenium homeostasis, liver pathology and tumor formation.
Finger JW Jr et al. Arch Environ Contam Toxicol 2018; (Epub) Dietary Selenomethionine Administration and Its Effects on the American Alligator (Alligator mississippiensis): Oxidative Status and Corticosterone Levels.
Application : WB
Reactivity : Alligator
Hyatt HW et al. Reprod Sci 2018;:1.93E+15 Changes in Metabolism, Mitochondrial Function, and Oxidative Stress Between Female Rats Under Nonreproductive and 3 Reproductive Conditions.
Application : WB
Reactivity : Rat
Zhang Y et al. J Exp Biol 2018; (Epub) High activity before breeding improves reproductive performance by enhancing mitochondrial function and biogenesis.
Application : WB
Reactivity : Mouse
You Y et al. J Hepatol 2018; (Epub) SNX10 mediates alcohol-induced liver injury and steatosis via regulating chaperone-mediated autophagy activation.
Application : WB
Reactivity : Mouse
Wu YL et al. Free Radic Biol Med 2018; 115:309-317 Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway.
Application : WB
Reactivity : Human
Hyatt HW et al. Sci Rep 2017; 7 (1):17118 Lactation has persistent effects on a mother's metabolism and mitochondrial function.
Application : WB
Reactivity : Rat
Chang CC et al. CNS Neurosci Ther 2017; (Epub) aβ exacerbates α-synuclein-induced neurotoxicity through impaired * signaling in α-synuclein-overexpressed human sk-n-mc neuronal cells.
Application : WB
Reactivity : Human
Finger JW Jr et al. Bull Environ Contam Toxicol 2017; (Epub) No Effect of Lifelong Methylmercury Exposure on Oxidative Status in Zebra Finches (Taeniopygia guttata): A Demonstration of Methylmercury-Induced Selection?
Application : WB
Reactivity : Bird
Zhang Y et al. Am J Physiol Regul Integr Comp Physiol 2017;:ajpregu.00176.2017 A mitohormetic response to pro-oxidant exposure in the house mouse.
Application : WB
Reactivity : Mouse
Brown JL et al. J Cachexia Sarcopenia Muscle 2017; (Epub) Mitochondrial degeneration precedes the development of muscle atrophy in progression of cancer cachexia in tumour-bearing mice.
Application : WB
Reactivity : Mouse
Chao W et al. Int Immunopharmacol 2017; 50:77-86 3, 4-dihydroxybenzalacetone attenuates lipopolysaccharide-induced inflammation in acute lung injury via down-regulation of MMP-2 and MMP-9 activities through suppressing ROS-mediated MAPK and PI3K/AKT signaling pathways.
Application : WB
Reactivity : Mouse
Lin WC et al. RSC Adv. 2017; 7:21234-21251 Anti-inflammatory activity of Sanghuangporus sanghuang by suppressing the TLR4-mediated PI3K/AKT/mTOR/IKKβ signaling pathway.
Application : WB
Reactivity : Mouse
Chao W et al. Molecules 2017; 22 (4) 3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NFκB Signaling Pathways.
Application : WB
Reactivity : Human
Salazar G et al. Free Radic Biol Med 2017; 108:225-235 Zinc regulates Nox1 expression through a NF-κB and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells.
Application : WB
Reactivity : Rat
Hyatt HW et al. Int J Physiol Pathophysiol Pharmacol 2016; 8 (4):160-168 Comparative changes in antioxidant enzymes and oxidative stress in cardiac, fast twitch and slow twitch skeletal muscles following endurance exercise training.
Hyatt HW et al. Int J Physiol Pathophysiol Pharmacol 2016; 8 (4):160-168 Comparative changes in antioxidant enzymes and oxidative stress in cardiac, fast twitch and slow twitch skeletal muscles following endurance exercise training.
Application : WB
Reactivity : Rat
Dai J et al. J Biol Inorg Chem 2016; 21 (8):1037-1046 Selenite and ebselen supplementation attenuates D-galactose-induced oxidative stress and increases expression of SELR and SEP15 in rat lens.
Application : WB
Reactivity : Rat
Mowry AV et al. PLoS One 2016; 11 (8):e0160883 Reproduction Does Not Adversely Affect Liver Mitochondrial Respiratory Function but Results in Lipid Peroxidation and Increased Antioxidants in House Mice.
Application : WB
Reactivity : Mouse
Feresin RG et al. Food Funct 2016; Blackberry, raspberry and black raspberry polyphenol extracts attenuate angiotensin II-induced senescence in vascular smooth muscle cells.
Application : WB
Reactivity : Rat
Brand S et al. PLoS One 2014; 9 (12):e115715 Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors.
Queisser N et al. Antioxid Redox Signal 2014; 21 (15):2126-42 Aldosterone activates transcription factor Nrf2 in kidney cells both in vitro and in vivo.
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