APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
2 μg/ml |
5 μg/ml |
Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
This STEAP4 antibody does not cross-react with other STEAP proteins.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A 14 amino acid synthetic peptide near the center of human STEAP4. The immunogen is located within amino acids 210 - 260 of STEAP4.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
STEAP4 metalloreductase , STAMP2 , STEAP4 , TIARP , TNFAIP9
Cellular Localization
Cell membrane,Golgi apparatus membrane
Background
The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]
Database
DATA IMAGES
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GTX85695 WB Image
WB analysis of rat liver tissue lysate using GTX85695 STEAP4 antibody. Dilution : 0.5 μg/mL (Lane A) and 1 μg/mL (Lane B)
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GTX85695 IHC-P Image
IHC-P analysis of human heart tissue using GTX85695 STEAP4 antibody. Antigen retrieval : Heat-induced antigen retrieval Dilution : 5 μg/ml
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REFERENCE
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REVIEW
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