GeneTex
United States (US)

STEP antibody [23E5]

GTX30465_1406_WB_18121410_998.jpg

Cat No. GTX30465

Host Mouse
Clonality Monoclonal
Clone Name 23E5
Isotype IgG1
Application WB, ICC/IF, IHC-Fr, IP, IHC
Reactivity Human, Mouse, Rat
See all STEP products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000 - 1:2000
ICC/IF 1:100 - 1:500
IHC-Fr 1:100 - 1:500
IP 1:50
IHC 1:100 - 1:500
Not tested in other applications.

Specificity/Sensitivity

This antibody is specific for STEP61, STEP46, STEP38, and STEP20.
PROPERTIES

Form

Liquid

Buffer

Ascites, 0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent(Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

A synthetic peptide of rat STEP46 (amino acids 57-74: MCTPGCNEEGFGYLVSPR)

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Cellular Localization

Cytoplasmic

Background

Tyrosine phosphorylation plays a critical role in many physiological processes. There is a fine balance between phosphorylation caused by protein tyrosine kinases and actions of protein tyrosine phosphatases, that regulates these physiological processes. Striatal enriched phosphatase (STEP) is part of a family of protein tyrosine phosphatases enriched within the CNS and is a component of the NMDAR complex. It is expressed within dopaminoceptive neurons in the CNS and particularly enriched within the basal ganglia and related structures.

Research Area

DATA IMAGES
GTX30465_1406_WB_18121410_998.jpg

GTX30465 WB Image

WB analysis of rat striatal protein homogenates using GTX30465 STEP antibody [23E5].
Package List Price ($)
$ 329