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STIM1 antibody [CDN3H4]

Anti-STIM1 antibody [CDN3H4] used in Western Blot (WB). GTX80195
Anti-STIM1 antibody [CDN3H4] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX80195

Cat. No. GTX80195

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CDN3H4

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, IP

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all STIM1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

77 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetized peptide (C-terminal cytoplasmic part of STIM1).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

D11S4896E , GOK , IMD10 , STIM1 , STRMK , TAM , TAM1 , stromal interaction molecule 1 , Stromal interaction molecule 1

Cellular Localization

Cell membrane,Endoplasmic reticulum membrane,Cytoplasm,Cytoskeleton

Background

This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES

Anti-STIM1 antibody [CDN3H4] used in Western Blot (WB). GTX80195

GTX80195 WB Image

WB analysis of RBL cell lysates (non-reducing) using GTX80195 STIM1 antibody [CDN3H4].
Lane 1 : GTX80195
Lane 2 : mouse IgG1 isotype control

Anti-STIM1 antibody [CDN3H4] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX80195

GTX80195 ICC/IF Image

ICC/IF analysis of methanol-aceton fixed HeLa cells using GTX80195 STIM1 antibody [CDN3H4].
Red : Primary antibody
Blue : DAPI

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399