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SULF2 antibody [2B4], C-term

Anti-SULF2 antibody [2B4], C-term used in IHC (Paraffin sections) (IHC-P). GTX38989

Cat. No. GTX38989

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2B4

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($409)
See all SULF2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

100 kDa. ( Note )

Product Note

This antibody recognizes Sulfatase 2, showing no cross-reactivity with Sulfatase 1 in either human or mouse.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human Sulf-2.

Purification

Protein G purified

Conjugation

Unconjugated

RRID

AB_11176271

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sulfatase 2 , HSULF-2

Cellular Localization

Endoplasmic reticulum

Background

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES

Anti-SULF2 antibody [2B4], C-term used in IHC (Paraffin sections) (IHC-P). GTX38989

GTX38989 IHC-P Image

IHC-P analysis of HEK293 cells transfected with SULF2 cells using GTX38989 SULF2 antibody [2B4], C-term.

REFERENCE

Application Reference

Yang L et al. Cereb Cortex 2019; 29 (2) : 838-851 Transcriptomic Landscape of von Economo Neurons in Human Anterior Cingulate Cortex Revealed by Microdissected-Cell RNA Sequencing.
Application : WB, ICC/IF
Reactivity : Human
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409