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SorLA antibody [3B6B11]

Anti-SorLA antibody [3B6B11] used in IHC (Paraffin sections) (IHC-P). GTX83063
Anti-SorLA antibody [3B6B11] used in IHC (Paraffin sections) (IHC-P). GTX83063
Anti-SorLA antibody [3B6B11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83063
Anti-SorLA antibody [3B6B11] used in Western Blot (WB). GTX83063

Cat. No. GTX83063

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3B6B11

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all SorLA products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ICC/IF 1/200 - 1/1000
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

248 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human SorLA expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sortilin related receptor 1 , C11orf32 , LR11 , LRP9 , SORLA , SorLA-1 , gp250

Cellular Localization

Membrane,Golgi apparatus,Endosome,Secreted

Background

This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of this locus and Alzheimer's Disease.[provided by RefSeq, Sep 2010]

Database

Research Area

DATA IMAGES

Anti-SorLA antibody [3B6B11] used in IHC (Paraffin sections) (IHC-P). GTX83063

GTX83063 IHC-P Image

IHC-P analysis of human cerebrum tissue using GTX83063 SorLA antibody [3B6B11].

Anti-SorLA antibody [3B6B11] used in IHC (Paraffin sections) (IHC-P). GTX83063

GTX83063 IHC-P Image

IHC-P analysis of human brain, cortex tissue using GTX83063 SorLA antibody [3B6B11].

Anti-SorLA antibody [3B6B11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83063

GTX83063 ICC/IF Image

ICC/IF analysis of PANC-1 cells using GTX83063 SorLA antibody [3B6B11].
Green : SorLA
Blue: DRAQ5 fluorescent DNA dye
Red: Actin filaments

Anti-SorLA antibody [3B6B11] used in Western Blot (WB). GTX83063

GTX83063 WB Image

WB analysis of truncated SorLA recombinant protein using GTX83063 SorLA antibody [3B6B11].

REFERENCE

Application Reference

Yang W et al. Cell Commun Signal 2021; 19 (1) : 112 Presenilin1 inhibits glioblastoma cell invasiveness via promoting Sortilin cleavage.
Reactivity : Human
Submit a Reference

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399