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TIA1 antibody [TIA1/1313]

Anti-TIA1 antibody [TIA1/1313] used in Western Blot (WB). GTX35120

Cat. No. GTX35120

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 TIA1/1313

Isotype

 IgG2b

Application

 WB, ICC/IF, FACS

Reactivity

 Human
Package
100 μg ($529)
See all TIA1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml for 60 minutes at RT
ICC/IF 1-2μg/ml
FACS 0.5-1μg/10⁶ cells in 0.1ml
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human TIA1 fragment of 102 amino acid residues (aa279-380)

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TIA1 , TIA1 cytotoxic granule associated RNA binding protein , WDM

Cellular Localization

Cytoplasm,Stress granule,Nucleus

Background

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. [provided by RefSeq, May 2017]

Database

Research Area

DATA IMAGES

Anti-TIA1 antibody [TIA1/1313] used in Western Blot (WB). GTX35120

GTX35120 WB Image

WB analysis of HepG2, PC3, and HeLa cell lysates using GTX35120 TIA1 antibody [TIA1/1313].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529