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TLR5 antibody

Anti-TLR5 antibody used in Flow cytometry (FACS). GTX13868
Anti-TLR5 antibody used in IHC (Paraffin sections) (IHC-P). GTX13868

Cat. No. GTX13868

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human, Mouse, Rat, Pig
Package
100 μl ($399)
See all TLR5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 3 μg/ml
IHC-P 10 μg/ml
FACS 1 - 2 μg / 10⁶ cells
Not tested in other applications.

Calculated MW

98 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This antibody was developed against KLH-conjugated synthetic peptide corresponding to a portion of human TLR5 found between amino acids 300-350. It will cross-react with mouse and rat TLR5.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

toll like receptor 5 , MELIOS , SLE1 , SLEB1 , TIL3

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-TLR5 antibody used in Flow cytometry (FACS). GTX13868

GTX13868 FACS Image

FACS (Intracellular staining) analysis of mouse splenocytes using GTX13868 TLR5 antibody.
Red : Primary antibody
Green : isotype control
Shaded histogram : cell only
Dilution : 2 μg/10⁶ cells

Anti-TLR5 antibody used in IHC (Paraffin sections) (IHC-P). GTX13868

GTX13868 IHC-P Image

IHC-P analysis of human stomach tumor tissue using GTX13868 TLR5 antibody.
Dilution : 10 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399