GeneTex
United States (US)

TPO protein

Cat No. GTX29719

Reactivity Human
Species Human
APPLICATION

Positive Control

Recombinant hIL-11 (ab
PROPERTIES

Form

Lyophilized powder

Buffer

Lyophilized from 10mM Tris, pH 8.0.

Storage

The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20 ºC. We recommend a quick spin followed by reconstitution in 10 mM Tris, pH 8.0 to a concentration of 0.5-1.0 mg/ml. This solution can then be diluted into

Antigen Species

Human

Immunogen

Highly pure (>98%) recombinant hIL-11 (human Interleukin-11)

Region/Sequence

Highly pure (>98%) recombinant hIL-11 (human Interleukin-11)

Purification


Sterile filtered Greater than 98% pure by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Thyroid Peroxidase,Msa,Tdh2A,Tpx,Tpo

Background

TPO acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined.

Research Area

Package List Price ($)
$ 239