GeneTex
United States (US)

TRAIL recombinant protein

TRAILApo2L-recombinant-protein_WB_GTX65295-1_18121411_990.jpg

Cat No. GTX65295

Application WB, ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The activity is determined by its ability to induce apoptotic cell death in TRAIL-sensitive U343MG cells. The ED50 for the effect is 1-3 ng/ml.

Calculated MW

19.6 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute in water to a concentration of 0.5-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or –20ºC for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tnf Superfamily Member 10,Apo2L,Apo-2L,Cd253,Tl2,Tnlg6A,Trail,Tnfsf10

Background

Human TRAIL (TNF-Related Apoptosis Inducing Ligand), also called Apo2 Ligand (Apo2L), is a cytotoxic protein that activates rapid apoptosis in tumor cells, but not at normal cells. The recombinant human TRAIL/Apo2L is a single polypeptide chain containing 168 amino acids and has a molecular mass of 19.6 kDa.

Research Area

DATA IMAGES
TRAILApo2L-recombinant-protein_WB_GTX65295-1_18121411_990.jpg

GTX65295 WB Image

SDS-PAGE (15%) of purified TRAIL/Apo2 Ligand:
Lane 1: Marker.
Lane 2: TRAIL/Apo2 Ligand -- 20 µg

Package List Price ($)
$ 199