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TRESK antibody

Anti-TRESK antibody used in IHC (Paraffin sections) (IHC-P). GTX85212
Anti-TRESK antibody used in IHC (Paraffin sections) (IHC-P). GTX85212
Anti-TRESK antibody used in Western Blot (WB). GTX85212

Cat. No. GTX85212

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all TRESK products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

Positive Control

Rat Brain Tissue Lysate(GTX27942)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TRESK antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRESK.The immunogen is located within amino acids 210 - 260 of TRESK.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

potassium two pore domain channel subfamily K member 18 , K2p18.1 , MGR13 , TRESK , TRESK-2 , TRESK2 , TRIK

Cellular Localization

Cell membrane

Background

TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.

Database

Research Area

DATA IMAGES

Anti-TRESK antibody used in IHC (Paraffin sections) (IHC-P). GTX85212

GTX85212 IHC-P Image

IHC-P analysis of rat brain tissue using GTX85212 TRESK antibody.
Working concentration : 5 μg/ml

Anti-TRESK antibody used in IHC (Paraffin sections) (IHC-P). GTX85212

GTX85212 IHC-P Image

IHC-P analysis of rat brain tissue using GTX85212 TRESK antibody.
Working concentration : 20 μg/ml

Anti-TRESK antibody used in Western Blot (WB). GTX85212

GTX85212 WB Image

WB analysis of rat brain tissue lysate using GTX85212 TRESK antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399