GeneTex
United States (US)

TRPC6 antibody, C-term

GTX88602_2210_WB_18122102_674.jpg

Cat No. GTX88602

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.03-0.1μg/ml
Not tested in other applications.

Calculated MW

106 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88602-PEP).

Predict Reactivity

Bovine(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-EKLSMEPNQEETNR, from the C Terminus of the protein sequence according to NP_004612.2.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Transient Receptor Potential Cation Channel Subfamily C Member 6,Fsgs2,Trp6,Trpc6

Background

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]

Database

Research Area

DATA IMAGES
GTX88602_2210_WB_18122102_674.jpg

GTX88602 WB Image

WB analysis of human placenta lysate using GTX88602 TRPC6 antibody, C-term.
Dilution : 0.03µg/ml
Loading : 35µg protein in RIPA buffer

Package List Price ($)
$ 329