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TRPM7 antibody

Anti-TRPM7 antibody used in IHC (Paraffin sections) (IHC-P). GTX20729

Cat. No. GTX20729

Reference 1

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Mouse, Rat
Package
100 μg ($399)
See all TRPM7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P 4-6μg/ml

Note :

IHC-P
Mouse Brain shows neuronal staining in the Hippocampus.
Not tested in other applications.

Calculated MW

213 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX20729-PEP).

Predict Reactivity

Human, Dog, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-TKESESTNSVRLML, from the C Terminus of the protein sequence according to NP_060142.3.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

RRID

AB_369434

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transient receptor potential cation channel subfamily M member 7 , ALSPDC , CHAK , CHAK1 , LTRPC7 , LTrpC-7 , TRP-PLIK

Cellular Localization

Membrane

Background

This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-TRPM7 antibody used in IHC (Paraffin sections) (IHC-P). GTX20729

GTX20729 IHC-P Image

IHC-P analysis of mouse hippocampus using GTX20729 TRPM7 antibody.
Antigen retrieval : citrate buffer pH 6
Dilution : 4μg/ml

REFERENCE

Application Reference

Chyau CC et al. J Ethnopharmacol 2014; 153 (3) : 650-8 mycelia glycoproteins from cordyceps sobolifera ameliorate *-induced renal tubule dysfunction in rats.
Application : WB, IHC-P
Reactivity : Rat
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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399