GeneTex
United States (US)

TWEAK recombinant protein

Cat No. GTX65293

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 10 ng/ml.

Calculated MW

17.0 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Buffer

10 mM Sodium Phosphate, pH 7.5 + 0.1 M L-Arg.

Storage

Reconstitute in 10 mM Sodium Phosphate (pH 7.5) to a concentration of 1 mg/ml. This solution can then be diluted into other aqueous buffers. Reconstitute in ddH2O. Store at -20ºC. Product is stable for at least 12 months.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tnf Superfamily Member 12,Apo3L,Dr3Lg,Tnlg4A,Tweak,Tnfsf12

Background

Human TWEAK is a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. TWEAK, like many other members of the TNF family, is able to induce interleukin-8 synthesis in a number of cell lines. The recombinant human TWEAK is a 17.0 kDa protein, comprising the TNF-like extraCellular domain of TWEAK

Research Area