GeneTex
United States (US)

Tau (phospho Thr231) antibody [13B10]

Cat No. GTX16052

Host Mouse
Clonality Monoclonal
Clone Name 13B10
Isotype IgM
Application WB, IP, ELISA
Reactivity Human
APPLICATION

Application Note

ELISA (recommended work dilution= 1:2,000-5,000); Western Blotting( recommended work dilution= 5 μg/ml); Immunoprecipitation (recommended work dilution= (mg/ml) Determined by customer)

Calculated MW

79 kDa. ( Note )

Specificity/Sensitivity

The antibody secreted by clone 13B10 specifically detected phosphorylated Tau protein derived from human brain tissue. It recognized PHF-tau phosphorylated at Thr231.In both ELISA and WB, this antibody shows no cross-reactivity with other unrelated proteins.
PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic peptide derived from human Tau

Purification

The IgM fraction of cell culture supernatant was purified by affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Microtubule Associated Protein Tau,Ddpac,Ftdp-17,Maptl,Mstd,Mtbt1,Mtbt2,Ppnd,Ppp1R103,Tau,Mapt

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

Database

Research Area

SDS
PBS.pdf
Package List Price ($)
$ 319