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Thrombin Receptor (cleaved Ser42) antibody

Anti-Thrombin Receptor (cleaved Ser42) antibody used in Western Blot (WB). GTX86903

Cat. No. GTX86903

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all Thrombin Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

Product Note

Thrombin Receptor (cleaved Ser42) antibody detects endogenous levels of fragment of activated Thrombin Receptor resulting from cleavage adjacent to Ser42.

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Thrombin Receptor (23-72).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CF2R , F2R , HTR , PAR1 , TR , coagulation factor II thrombin receptor , Thrombin Receptor

Cellular Localization

Cell membrane

Background

Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Database

Research Area

DATA IMAGES

Anti-Thrombin Receptor (cleaved Ser42) antibody used in Western Blot (WB). GTX86903

GTX86903 WB Image

WB analysis of Jurkat cell lysates using GTX86903 Thrombin Receptor (cleaved Ser42) antibody. The lane on the right is blocked with the synthesized peptide.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399