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Thrombomodulin antibody [15C8]

Anti-Thrombomodulin antibody [15C8] used in IHC (Paraffin sections) (IHC-P). GTX01950

Cat. No. GTX01950

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 15C8

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($589)
See all Thrombomodulin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to the epidermal growth factor homology domain of the human CD141 molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

thrombomodulin , AHUS6 , BDCA3 , CD141 , THPH12 , THRM , TM

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Thrombomodulin antibody [15C8] used in IHC (Paraffin sections) (IHC-P). GTX01950

GTX01950 IHC-P Image

IHC-P analysis of human tonsil using GTX01950 Thrombomodulin antibody [15C8]. Note membrane staining of the basal cells of the squamous mucosa, endothelium and a subset of dentritic cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 589