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Transgelin antibody

Anti-Transgelin antibody used in IHC (Paraffin sections) (IHC-P). GTX33555
Anti-Transgelin antibody used in Western Blot (WB). GTX33555
Anti-Transgelin antibody used in Western Blot (WB). GTX33555
Anti-Transgelin antibody used in IHC (Paraffin sections) (IHC-P). GTX33555

Cat. No. GTX33555

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Transgelin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human TAGLN (NP_001001522.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transgelin , SM22 , SM22-alpha , SMCC , TAGLN1 , WS3-10

Cellular Localization

Cytoplasm

Background

This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-Transgelin antibody used in IHC (Paraffin sections) (IHC-P). GTX33555

GTX33555 IHC-P Image

IHC-P analysis of human colon tissue using GTX33555 Transgelin antibody.
Antigen retrieval : high-pressure antigen retrieval with 10mM citrate buffer (pH 6.0)
Dilution : 1:20

Anti-Transgelin antibody used in Western Blot (WB). GTX33555

GTX33555 WB Image

WB analysis of rat uterus tissue lysate using GTX33555 Transgelin antibody.
Dilution : 1:500
Loading : 25μg per lane

Anti-Transgelin antibody used in Western Blot (WB). GTX33555

GTX33555 WB Image

WB analysis of mouse uterus tissue lysate using GTX33555 Transgelin antibody.
Dilution : 1:500
Loading : 25μg per lane

Anti-Transgelin antibody used in IHC (Paraffin sections) (IHC-P). GTX33555

GTX33555 IHC-P Image

IHC-P analysis of human placenta tissue using GTX33555 Transgelin antibody.
Antigen retrieval : high-pressure antigen retrieval with 10mM citrate buffer (pH 6.0)
Dilution : 1:20

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399