GeneTex
United States (US)

VEGF protein

Cat No. GTX29954

Reactivity Human
Species Mouse
PRODUCT

Product Description

Vascular Endothelial Growth Factor Mouse Recombinant produced in E.Coli is a double, non-glycosylated, polypeptide chain containing 165 (each chain) amino acids and having a molecular mass of 39kDa. The VEGF is purified by proprietary chromatographic techniques.
PROPERTIES

Form

Lyophilized powder

Storage

Lyophilized Vascular Endothelial Growth Factor although stable at room temperature for 3 weeks, should be stored desiccated below -18ºC. Upon reconstitution VEGF should be stored at 4ºC between 2-7 days and for future use below -18ºC.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Region/Sequence

MAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR.

Purification


Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Cellular Localization

Secreted

Background

VEGF (Vascular Endothelial Growth Factor) is a homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. It exhibits potent mitogenic and permeability inducing properties specific for the vascular endothelium. Of the four isoforms of VEGF, the smaller two, VEGF 165 and VEGF 121, are secreted proteins and act as diffusible agents, whereas the larger two (VEGF 189 and VEGF 206) remain cell associated.
Package List Price ($)
$ 299