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United States (US)

XPA antibody [5A2]

Cat No. GTX20044

Host

Mouse

Clonality

Monoclonal

Clone Name

5A2

Isotype

IgG1

Application

WB, ICC/IF, Dot, ELISA, Immunoassay

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

Western blot: 1:1,000 - 1:1,500 Optimal dilutions/concentrations should be determined by the end user

Calculated MW

31 kDa. ( Note )

Positive Control

LS174T or MCF-7 cells, or human tonsil

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human XPA (Xeroderma Pigmentosum group A) protein

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

XPA, DNA damage recognition and repair factor , XP1 , XPAC

Cellular Localization

Nucleus

Background

This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017]

Database

Research Area

REFERENCE

There are currently no references for XPA antibody [5A2] (GTX20044). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 339
Custom Conjugations