GeneTex
  • Country / Location Selection

United States (US)

XRCC3 antibody [XRCC3 10F1/6]

Cat No. GTX40254

Host

Mouse

Clonality

Monoclonal

Clone Name

XRCC3 10F1/6

Isotype

IgG1

Application

WB

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

For WB: Use at an assay dependent dilution. Detects a band of approximately 37.8 kDa. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

38 kDa. ( Note )

Positive Control

Does not recognise XRCC3 in HeLa total extracts- suggest nuclear extracts

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length Human XRCC3 (his-tagged) overexpressed in E.coli and purified on a talon affinity column under denaturing conditions, followed by gel purification on a SDS-Page.

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

X-ray repair cross complementing 3 , CMM6

Cellular Localization

Nucleus , Cytoplasm , Mitochondrion

Background

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

REVIEW

There are currently no reviews for XRCC3 antibody [XRCC3 10F1/6] (GTX40254). Be the first to share your experience with this product.
Package List Price ($)
$ 339
Custom Conjugations