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ZIP3 antibody

Anti-ZIP3 antibody used in Western Blot (WB). GTX85133
Anti-ZIP3 antibody used in IHC (Paraffin sections) (IHC-P). GTX85133

Cat. No. GTX85133

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all ZIP3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

Positive Control

Mouse Small Intestine Tissue Lysate(GTX27939)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

ZIP3 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP3.The immunogen is located within amino acids 110 - 160 of ZIP3.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 39 member 3 , ZIP-3 , ZIP3

Cellular Localization

Membrane

Background

The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3- mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.

Database

Research Area

DATA IMAGES

Anti-ZIP3 antibody used in Western Blot (WB). GTX85133

GTX85133 WB Image

WB analysis of mouse lung tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX85133 ZIP3 antibody.
Working concentration : 1 μg/ml

Anti-ZIP3 antibody used in IHC (Paraffin sections) (IHC-P). GTX85133

GTX85133 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX85133 ZIP3 antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399