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alpha 2c Adrenergic Receptor antibody

Anti-alpha 2c Adrenergic Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX71447

Cat. No. GTX71447

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Monkey
Package
25 μg ($299)
See all alpha 2c Adrenergic Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 26 μg/ml
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Predict Reactivity

Rat, Dog, Guinea pig, Gibbon, Gorilla(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 18 amino acid peptide from N-terminal extracellular domain of human ADRA2C.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_375745

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

adrenoceptor alpha 2C , ADRA2C , ADRA2L2 , ADRA2RL2 , ADRARL2 , ALPHA2CAR , alpha 2c Adrenergic Receptor

Cellular Localization

Cell membrane

Background

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-alpha 2c Adrenergic Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX71447

GTX71447 IHC-P Image

IHC-P analysis of human artery, smooth muscle tissue using GTX71447 alpha 2c Adrenergic Receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 299