GeneTex

  • Country / Location Selection

United States (US)

alpha Sarcoglycan antibody

Orthogonal
Anti-alpha Sarcoglycan antibody used in Western Blot (WB). GTX87192
Anti-alpha Sarcoglycan antibody used in Western Blot (WB). GTX87192
Anti-alpha Sarcoglycan antibody used in IHC (Paraffin sections) (IHC-P). GTX87192

Cat. No. GTX87192

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all alpha Sarcoglycan products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human alpha Sarcoglycan (161-210).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

RRID

AB_10724428

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

50DAG , ADL , DAG2 , DMDA2 , LGMD2D , SCARMD1 , SGCA , adhalin , sarcoglycan alpha , alpha Sarcoglycan

Cellular Localization

Cell membrane,Sarcolemma,Cytoplasm,Cytoskeleton

Background

This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-alpha Sarcoglycan antibody used in Western Blot (WB). GTX87192

GTX87192 WB Image

WB analysis of HeLa, HepG2, and Jurkat cell lysates using GTX87192 alpha Sarcoglycan antibody. The lane on the right is blocked with the synthesized peptide.

Anti-alpha Sarcoglycan antibody used in Western Blot (WB). GTX87192

GTX87192 WB Image

Orthogonal

The data was published in the journal Int J Mol Sci in 2019.PMID: 31689918

Anti-alpha Sarcoglycan antibody used in IHC (Paraffin sections) (IHC-P). GTX87192

GTX87192 IHC-P Image

Orthogonal

The data was published in the journal Int J Mol Sci in 2019.PMID: 31689918

REFERENCE

Application Reference

Perez-Ortiz AC et al. Int J Mol Sci 2019; 20 (21) Lack of Delta-Sarcoglycan (Sgcd) Results in Retinal Degeneration.
Application : IHC-P
Reactivity : Mouse
Estrada-Mena FJ et al. Neurosci Lett 2017; 658 : 142-149 Effects of (-)-epicatechin on frontal cortex DAPC and dysbindin of the mdx mice.
Application : WB
Reactivity : Mouse
Submit a Reference

REVIEW

There are currently no reviews for alpha Sarcoglycan antibody (GTX87192). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399