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beta Arrestin 1 antibody

Anti-beta Arrestin 1 antibody used in Immunoprecipitation (IP). GTX30065
Anti-beta Arrestin 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30065
Anti-beta Arrestin 1 antibody used in Western Blot (WB). GTX30065
Anti-beta Arrestin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX30065
Anti-beta Arrestin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX30065

Cat. No. GTX30065

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IP

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all beta Arrestin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:20 - 1:100
IHC-P 1:50 - 1:200
IP 1:50 - 1:100
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 169-418 of human ARRB1 (NP_004032.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

arrestin beta 1 , ARB1 , ARR1

Cellular Localization

Cytoplasm,Nucleus,Cell membrane,Cytoplasmic vesicle

Background

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]

Database

Research Area

DATA IMAGES

Anti-beta Arrestin 1 antibody used in Immunoprecipitation (IP). GTX30065

GTX30065 IP Image

IP analysis of K-562 cell lysate using GTX30065 beta Arrestin 1 antibody.
Antibody amount : 3μg / 200μg lysate
Dilution : 1:1000

Anti-beta Arrestin 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30065

GTX30065 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX30065 beta Arrestin 1 antibody.
Blue : DAPI

Anti-beta Arrestin 1 antibody used in Western Blot (WB). GTX30065

GTX30065 WB Image

WB analysis of various sample lysates using GTX30065 beta Arrestin 1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-beta Arrestin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX30065

GTX30065 IHC-P Image

IHC-P analysis of mouse spleen tissue using GTX30065 beta Arrestin 1 antibody.
Dilution : 1:100

Anti-beta Arrestin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX30065

GTX30065 IHC-P Image

IHC-P analysis of rat heart tissue using GTX30065 beta Arrestin 1 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399