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mAChR M2 antibody [2-1-155]

Cat. No. GTX78911

Host

 Rat

Clonality

 Monoclonal

Clone Name

 2-1-155

Isotype

 IgG1

Application

 IHC-Fr

Reactivity

 Human, Mouse, Rat, Monkey
Package
100 μg ($399)
See all mAChR M2 products

APPLICATION

Application Note

Recommended Starting Dilutions:
For IHC: Use at 1-3 μg/ml
Not yet tested in other applications. Optimal dilutions should be determined experimentally by the researcher.

Calculated MW

52 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

The I3 loop of the M2 receptor fusion protein (residues 225-359) was expressed as a GST fusion protein

Purification

Protein A/G purified

Conjugation

Unconjugated

RRID

AB_11179706

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cholinergic receptor muscarinic 2 , HM2

Cellular Localization

Cell membrane

Background

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399