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p53 antibody [IHC053]

Anti-p53 antibody [IHC053] used in IHC (Paraffin sections) (IHC-P). GTX57208

Cat. No. GTX57208

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 IHC053

Isotype

 IgG2b

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($399)
See all p53 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

Positive Control

Colon Carcinoma

PROPERTIES

Form

Liquid

Buffer

Tris buffer, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human p53 protein.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Tumor Protein P53 , Bcc7 , Lfs1 , P53 , Trp53 , Tp53

Background

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]

Research Area

DATA IMAGES

Anti-p53 antibody [IHC053] used in IHC (Paraffin sections) (IHC-P). GTX57208

GTX57208 IHC-P Image

IHC-P analysis of human colon cancer tissue using GTX57208 p53 antibody [IHC053]

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399