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proBNP antibody [11D1]

Anti-proBNP antibody [11D1] used in Western Blot (WB). GTX13059
Anti-proBNP antibody [11D1] used in Western Blot (WB). GTX13059

Cat. No. GTX13059

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 11D1

Isotype

 IgG1

Application

 WB, ELISA

Reactivity

 Human
Package
200 μg ($399)
See all BNP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

15 kDa. ( Note )

Product Note

NT-proBNP and proBNP

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic N-terminal pro brain natriuretic peptide (NT-proBNP), corresponding to amino acid residues a.a.r. 28-45. The peptides used for immunization were conjugated with carrier protein.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

natriuretic peptide B , BNP

Cellular Localization

Secreted

Background

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]

Database

Research Area

DATA IMAGES

Anti-proBNP antibody [11D1] used in Western Blot (WB). GTX13059

GTX13059 WB Image

Detection of human recombinant NT-proBNP expressed in E. coli in Western blotting by different monoclonal antibodies after Tricine-SDS gel electrophoresis. Antigen: recombinant NT-proBNP expressed in E. coli, 2.5 ug; Lane 1: proBNP antibody [5B6] (GTX13111); Lane 2: proBNP antibody [15F11] (GTX13115); Lane 3: proBNP antibody [11D1] (GTX13059); Lane 4: proBNP antibody [24E11] (GTX13123)

Anti-proBNP antibody [11D1] used in Western Blot (WB). GTX13059

GTX13059 WB Image

Detection of human recombinant proBNP expressed mammalian cells in Western blotting by different monoclonal antibodies after Tricine-SDS gel electrophoresis. Antigen: recombinant proBNP expressed in mammalian cells, 0.15 ug; Lane 1: proBNP antibody [5B6] (GTX13111); Lane 2: proBNP antibody [15F11] (GTX13115); Lane 3: proBNP antibody [3G12] (GTX14712); Lane 4: proBNP antibody [11D1] (GTX13059); Lane 5: proBNP antibody [24E11] (GTX13123); Both proBNP antibody [11D1] (GTX13059) and proBNP antibody [24E11] (GTX13123)do not recognize glycosylated proBNP expressed in mammalian cells.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399