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EXOSC8 antibody

Anti-EXOSC8 antibody used in Western Blot (WB). GTX118146
Anti-EXOSC8 antibody used in Western Blot (WB). GTX118146
Anti-EXOSC8 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX118146

Cat. No. GTX118146

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all EXOSC8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
Not tested in other applications.

Calculated MW

30 kDa. ( Note )

Positive Control

HepG2 , Jurkat , Raji , NCI-H929

Predict Reactivity

Mouse, Bovine, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.42 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human EXOSC8. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10617882

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

exosome component 8 , CIP3 , EAP2 , OIP2 , PCH1C , RRP43 , Rrp43p , bA421P11.3 , p9

Cellular Localization

Cytoplasm , Nucleus , nucleolus

Background

This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-EXOSC8 antibody used in Western Blot (WB). GTX118146

GTX118146 WB Image

Sample (30 ug of whole cell lysate)
A: HepG2
12% SDS PAGE
GTX118146 diluted at 1:1000

Anti-EXOSC8 antibody used in Western Blot (WB). GTX118146

GTX118146 WB Image

EXOSC8 antibody detects EXOSC8 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with EXOSC8 antibody (GTX118146) diluted by 1:1000.

Anti-EXOSC8 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX118146

GTX118146 ICC/IF Image

Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using EXOSC8(GTX118146) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with GTX11304 (Red) at 1:2000.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169