APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:10,000 |
1:100 |
Assay dependent |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
chicken fibroblast, MDCK
Product Note
Reacts specifically with the N-terminal region of p120ctn and recognizes isoforms 1 and 2, but not isoforms 3 or 4. In immunoblotting, the antibody recognizes a 120 kDa band, and an additional very weak doublet at 200 kDa.
PROPERTIES
Form
Liquid
Buffer
Tissue culture supernatant
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Mouse
Immunogen
recombinant N-terminal fragment of murine p120ctn.[1]
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
catenin (cadherin associated protein), delta 1 , AA409437 , AU019353 , Catns , Ctnnd , P120 , mKIAA0384
Cellular Localization
Cytoplasm,Nucleus,Cell membrane
Background
delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
Database
Research Area
REFERENCE
There are currently no references for p120 Catenin antibody [6H11] (GTX11508). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for p120 Catenin antibody [6H11] (GTX11508). Be the first to share your experience with this product.