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SPNS2 antibody, N-term

Anti-SPNS2 antibody, N-term used in Western Blot (WB). GTX45115

Cat. No. GTX45115

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human
Package
50 μg ($419)
See all SPNS2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
ICC/IF Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Positive Control

human fetal muscle

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide locates within AA71-120 of human SPNS2.

Purification

Affinity Purified

Conjugation

Unconjugated

RRID

AB_11172128

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sphingolipid transporter 2

Cellular Localization

Membrane

Background

The protein encoded by this gene is a transporter of sphingosine 1-phosphate, a secreted lipid that is important in cardiovascular, immunological, and neural development. Defects in this gene are a cause of early onset progressive hearing loss. [provided by RefSeq, Jul 2016]

Database

Research Area

DATA IMAGES

Anti-SPNS2 antibody, N-term used in Western Blot (WB). GTX45115

GTX45115 WB Image

WB analysis of human fetal muscle tissue using GTX45115 SPNS2 antibody at 0.2-1μg/ml.

REFERENCE

Application Reference

Zulueta A et al. Biomedicines 2021; 9 (9) Spns2 Transporter Contributes to the Accumulation of S1P in Cystic Fibrosis Human Bronchial Epithelial Cells.
Application : IHC-P
Reactivity : Human
Tran HB et al. PLoS One 2017; 12 (11) : e0179577 Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD.
Application : ICC/IF
Reactivity : Human
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419